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    Please use this identifier to cite or link to this item: https://ir.fy.edu.tw:8080/ir/handle/987654321/15795


    Title: The effect of butanolides from Cinnamomum tenuifolium on platelet aggregation
    Authors: 陳中一
    Contributors: 輔英科技大學 保健營養系
    Keywords: Cinnamomum tenuifolium;isotenuifolide;tenuifolide B;platelet aggregation
    Date: 2013-10-01
    Issue Date: 2014-08-14 16:33:39 (UTC+8)
    Abstract: This study investigated the effects of isotenuifolide and tenuifolide B from the stems of Cinnamomum tenuifolium on adenosine diphosphate (ADP)-induced human platelet aggregation. Treatment of human platelet-rich plasma with isotenuifolide (1 and 2 μg/μL) and tenuifolide B (1, 2 and 4 μg/μL) did not have any significant effect on human platelet aggregation in vitro, however, treatment of human platelet-rich plasma with isotenuifolide (4 μg/μL) resulted in an inhibitory effect on platelet aggregation, suggesting the potential of this compound as an anti-atherosclerogenic agent in humans. Isotenuifolide is a new butanolide compound, whose structure was characterized by spectral analyses.
    Relation: Molecules 18(10),11836-11841
    Appears in Collections:[保健營養系] 期刊論文

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