The separation and migration behavior of six isomeric dichlorophenols (DCPs) in cyclodextrin-modified capillary zone electrophoresis (CD-CZE) using a phosphate-borate buffer at alkaline pH with β-CD and hydroxypropyl-β-CD (HP-β-CD) as electrolyte modifiers were investigated. The influence of buffer pH and the concentration of β-cyclodextrins were examined. The results indicate that baseline separation of six isomeric DCPs can be achieved with addition of β-CD concentration in the range of 2.0-10 mM or HP-β-CD concentration in the range of 4.0-10 mM at pH 10.0. Binding constants of DCPs to β-CDs were evaluated for a better understanding of the interaction of DCPs with β-CDs.
Journal of the Chinese Chemical Society 61(9),1025-1030