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    Please use this identifier to cite or link to this item: https://ir.fy.edu.tw:8080/ir/handle/987654321/2528

    Title: Taiwan Infant Stool Color Card Study Group.Universal screening for biliary atresia using an infant stool color card in Taiwan
    Authors: Cheng-Hui Hsiao;Mei-Hwei Chang;Huey-Ling Chen;Hung-Chang Lee;Tzee-Chung Wu;Chieh-Chung Lin;Yao-Jong Yang;An-Chyi Chen;Mao-Meng Tiao;Beng-Huat La;Chia-Hsiang Chu;Ming-Wei Lai;the Taiwan Infant Stool Color Card Study Group
    Contributors: 輔英科技大學 護理系
    Date: 2007-12-20
    Issue Date: 2010-09-27 17:07:31 (UTC+8)
    Abstract: Biliary atresia is the most common cause of death from liver disease in children. Although the
    Kasai operation before 60 days of age can significantly improve prognosis, delay in referral and
    surgery remains a formidable problem worldwide because of difficulties in differentiating it from
    benign prolonged neonatal jaundice.Weestablished a universal screening system using an infant
    stool color card to promote the early diagnosis and treatment of biliary atresia. After a pilot
    regional study in 2002-2003, a national stool color screening system was established by integrating
    the infant stool color card into the child health booklet given to every neonate in Taiwan since
    2004. Within 24 hours of the discovery of an abnormal stool color, this event is reported to the
    registry center. The annual incidence of biliary atresia per 10,000 live births in 2004 and 2005
    was 1.85 (40/216,419) and 1.70 (35/205,854), respectively. The sensitivity of detecting biliary
    atresia using stool cards before 60 days of age was 72.5% in 2004, which improved to 97.1% in
    2005. The national rate of the Kasai operation before 60 days of age increased from 60% in 2004
    to 74.3% in 2005. The jaundice-free rate (<2 mg/dL) at 3 months after the Kasai operation
    among infants with biliary atresia in 2004-2005 was 59.5% (44 of 74), significantly higher than
    the historical data of 37.0% in 1976-2000 before the stool card screening program (P0.002).
    Conclusion: Universal screening using the stool color cards can enhance earlier referral, which
    may ultimately lead to timely performance of the Kasai operation and better postoperative
    outcome in infants with biliary atresia. (HEPATOLOGY 2008;47:1233-1240.)
    Relation: Hepatology 47(4),1233-1240
    Appears in Collections:[護理系] 期刊論文

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