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    题名: A seroepidemiology study of varicella among children aged 0-12 years in Taiwan
    作者: Tseng, H.F.;Tan, H.F.;Chang, C.K.;Wang, L.Y.;Yang, S.E.;Liau, M.Y.;Pan, M.J.;Chen, Chung-Yi;Huang, S.P.
    贡献者: 輔英科技大學 生物科技系
    日期: 2005-09-01
    上传时间: 2010-10-08 10:54:46 (UTC+8)
    摘要: The epidemiology pattern of varicella appears to vary among regions with different climates, population densities, and degrees of development. This study investigated the age-specific varicella zoster virus (VZV) seroprevalence in children aged 0 to 12 years in Taiwan and compared these seroprevalences between free and private vaccination areas. Residual sera were collected from 13 hospitals with 1,401 valid samples. Immunoglobulin G antibodies to VZV were measured by enzyme-linked immunosorbent assay. Parents of 656 children answered questions about the varicella incidence and varicella vaccination history of their children. In the 8-12 year-olds, the seroprevance ranged between 88.0-93.8% in northern, central, and eastern, while it was only 76.1% in southern Taiwan. The seroprevalence of children 0-5 years old were significantly different between free and private vaccination areas. Seropositive children who reported no history of varicella or receiving varicella vaccine accounted for 26.1-59.3% of the total positive cases. Our findings suggest the possible effects of climate, geographical conditions, and lifestyle on the seroepidemiology of VZV in Taiwan. The efforts of implementing a varicella vaccination program in Taiwan should focus on reaching high levels of coverage.
    關聯: Southeast Asian J Trop Med Public Health. 36(5):p.1201-7
    显示于类别:[生物科技系] 期刊論文


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