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    Please use this identifier to cite or link to this item: https://ir.fy.edu.tw:8080/ir/handle/987654321/8867


    Title: Chemical Constituents from the Whole Plant of Gaultheria itoana Hayata.
    Authors: Chen, Chung-Yi;Rong-Jyh Lin;Jin-Cherng Huang;Yi-Hung Wu;Ming-Jen Cheng;His-Chou Hung;Wen-Li Lo
    Contributors: 輔英科技大學 醫學檢驗生物技術系
    Keywords: Gaultheria itoana;Diterpenoids;Abietanes;Podocarpanes;Cytotoxic activity
    Date: 2009-10-01
    Issue Date: 2010-11-05
    Abstract: Two new diterpenoids, 14,18-dihydroxyabieta-8,11,13-trien-7-one (1) and 13-acetyl-14,18-dihydroxy-podocarpa-8,11,13-triene (2), together with eight known compounds, i.e., gaultheric acid (3), vanillic acid (4), 4-hydroxybenzoic acid (5), cinnamic acid (6), stearic acid (7), palmitic acid (8), β-sitosterol (9), and stigmasterol (10), were isolated from the MeOH extract of the whole plant of Gaultheria itoanaHayata (Ericaceae). The structures of the new constituents were elucidated by spectroscopic methods (UV, IR, and 1D- and 2D-NMR) and by mass spectrometry (HR-ESI-MS). Among them, 1 and 2 were demonstrated to exhibit significant cytotoxic activity against the LNCaP cell line.
    Relation: Chemistry & Biodiversity 6(10),1737-1743
    Appears in Collections:[醫學檢驗生物技術系] 期刊論文

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