English  |  正體中文  |  简体中文  |  Items with full text/Total items : 6047/14565 (42%)
Visitors : 13640327      Online Users : 340
RC Version 7.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
Scope Tips:
  • please add "double quotation mark" for query phrases to get precise results
  • please goto advance search for comprehansive author search
  • Adv. Search
    HomeLoginUploadHelpAboutAdminister Goto mobile version
    Please use this identifier to cite or link to this item: https://ir.fy.edu.tw:8080/ir/handle/987654321/9627


    Title: Lack of Association of Interleukin-6 and Interleukin-8 Gene Polymorphisms in Chinese Patients With Systemic Lupus Erythematosus.
    Authors: Chung-Ming Huang;An-Ping Huo;Chang-Hai Tsai;Chi-Lan Chen;Fuu-Jen Tsai
    Contributors: 輔英科技大學 健康美容學位學程
    Keywords: IL-6;IL-8;SLE;gene polymorphism
    Date: 2006-11-01
    Issue Date: 2010-11-11 11:21:43 (UTC+8)
    Abstract: The purpose of this study was to determine whether interleukin (IL)-6 and IL-8 gene polymorphisms were markers of susceptibility to or severity of systemic lupus erythematosus (SLE) in Chinese patients. The study included 150 Chinese patients with SLE. A total of 130 unrelated healthy individuals living in central Taiwan served as control subjects. Polymorphisms of the IL-6 and IL-8 gene were typed from genomic DNA. The genotypes, allelic frequencies, and carriage rates were compared between SLE patients and control subjects. The relationship between allelic frequencies and clinical manifestations of 135 SLE patients was evaluated. There were no statistically significant differences in IL-6 and IL-8 gene polymorphisms between the SLE and control groups (chi-squared test, P=0.53, χ2=1.27 and P=0.44, χ2=1.62, respectively). In addition, there was no significant association between the two groups in allelic frequency of IL-6 and IL-8 (P=0.89 and P=0.26, respectively). We also did not detect any association between the IL-6 and IL-8 genotype and clinical or laboratory profiles in SLE patients. The results suggest that the IL-6 and IL-8 gene polymorphisms are not related to SLE.
    Relation: Journal of Clinical Laboratory Analysis 20(6),255-259
    Appears in Collections:[健康美容系] 期刊論文

    Files in This Item:

    File Description SizeFormat
    index.html0KbHTML527View/Open


    All items in FYIR are protected by copyright, with all rights reserved.


    本網站典藏內容為學術研究目的之提供,請尊重著作權人之權益合理使用,請勿任意重製、轉貼、改作及散佈。

    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - Feedback